Particle Therapy 2017

Rubin,

Constine, et al

LENT scoring

IJROBP 1995

0-20% Dose (Gy) 0 20 40 60 70

10-50%

>20%

>75% 60-80%

>40%

<25%

>75%

10-25%

<15-20% 25-40% 25-

<5%

40%

<20%

<5%

>50%

5-10%

40-60% 5-25%

40-60% 10-20% 30-50%

15% 60-80% 15- 25%

<10%

>50%

10-

<5%

<5%

<1%

<1%

<5%

<5%

0-20%

0-20%

0-20%

0-20%

20-40%

40-60%

60-80%

20-40%

20-40%

40-60%

20-40%

60-80%

80-100%

80-100%

80-100%

80-100%

L

E

L

E

L

E

L

E

V

U

V

U

V

U

V

U

O

O

O

O

M

M

M

M

Live r

Lun g

Kidne y

cord

Heart

Risk of late toxicity as a function of radiation dose and volume Spinal

Toxicity is a function of radiation dose!