Particle Therapy 2017

Dealing with uncertainties

Robust optimisation – What is a good robustness metric?

IMPT plan to skull base chordoma

Single fraction dose uncertainties CI85% = 1.76mm

Full treatment dose uncertainties (37 fractions)

Fractionation

Worse case (1 fraction)

20 fractions

Albertini et al (2010)

Lowe et al (2016)