Particle Therapy 2017

Radiolysis of water !

h

ν

Indirect effects: Interaction of photons or electrons with water molecules. Result: Formation of radicals H2O H2O+ + e- Hydroxyl radical: H2O+ H2O H3O+ + OH- Solvated electrons: e- + [H20+] e-aqu. Hydroxyl radical: e-aqu. + H2O OH- Hydrogen peroxide: OH- + OH- H2O2

Effect of Ionizing Radiation on Biomolecules