Particle Therapy 2017

Limited Impact of Setup and Range Uncertainties, Breathing Motion, and Interplay Effects in Robustly Optimized Intensity Modulated Proton Therapy for Stage III Non- small Cell Lung Cancer. Inoue T, Langendijk J, Korevaar W et al Chiba, Osaka, Tokyo,, Japan., Groningen. IJROBP 96(3), 2016

10 NSCLC patients were planned using 3-field IMPT 4-D and average intensity projection CT images. 5- or 7-mm setup errors with ±3% range uncertainties The robustness evaluation: (1) isotropic 5-mm setup errors with ±3% range uncertainties; (2) breathing motion; (3) interplay effects (4) a combination of items 1 and 2. Comparison with volumetric modulated arc therapy plans.

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