Particle Therapy 2017

Re-irradiation:

➢ Considered strong indication. ➢ Multiple trials ongoing ➢ Issue: “cumulative dose of normal tissue” – how to deal with prior dose 1 year or 20 years ago (OAR dose constraint definition) ➢ Issue: Appropriate patient selection –i.e. who will benefit considering the risks?

Example: Int J Radiat Oncol Biol Phys. 2014 Nov 15;90(4):819-27. Definitive reirradiation for locoregionally recurrent non-small cell lung cancer with proton beam therapy or intensity modulated radiation therapy: predictors of high-grade toxicity and survival outcomes. McAvoy S1

RADCOMP CONSORTIUM

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