Physics Athens 2016

The inverse problem

“Independent” variables

Optimization can involve:

?

Beam intensity profiles Beam weights, segment weights Beam angles (gantry angle, couch angle) Number of beams Radiation energy (especially in particle therapy) Type of radiation (photons, electrons, ...) …

“How do we find the best solution among the millions of combinations of these parameters, which result in an optimal/adequate coverage of the target and sparing of OAR?”