Physics Bucharest 2017
IMRT: What are the Potential Weak Links?
MU-dose relationship is not intuitive Simple point dose verification calculations do not cover the properties of the whole dose distribution Inverse Treatment Planning The multiple constraints, (competing) objectives, and the numerous degrees of freedom make plan optimization a large scale multi- criteria, non-convex, combinatorial, and discrete problem and thereby not straightforward to solve. Mechanical accuracy of the linear accelerator Gantry, collimator, table iso-center (typically < 1 mm)
Ezzell G, Galvin JM, Low D, Palta JR, Rosen I, Sharpe MB, Xia P, Xiao Y, Xing L and Yu CX. Guidance document on delivery, treatment planning, and clinical implementation of IMRT: Report of the IMRT subcommittee of the AAPM Radiation Therapy Committee. Med. Phys. 30: 2090 – 2115, 2003
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