Physics Bucharest 2017

Early therapeutic radiation reactions

• Occur during or shortly after completion • Due to rapid cell loss • Associated with oedema and exudation • Seen in skin, gastrointestinal tract and bone marrow • Repair due to cell renewal via intact basal cells • Healing usually complete but can result in consequential late reactions . Seen in skin, bladder and oral mucosa when persistent damage remains long-term after severe acute damage