Physics Bucharest 2017
Homogeneity
Clinically relevant?
Conformality
Steep dose gradient
Applications
Examples
prostate (rectum), head neck (spinal cord), pelvis
I. Coverage of concave PTV with better sparing of OAR
nasopharyngeal, prostate, head-neck cancer,…
II. Better coverage of tumors near critical structures (also convex) III. Intentionally inhomogeneous dose distributions
SIB, multiple GTV/CTVs...
spine, head-neck,…
IV. Re-irradiation of locally recurrent tumors
brachytherapy
V. Compensation of plans
Potential of IMRT
→ delivery of conventional doses with ↓ toxicity → delivery of higher doses without ↑ toxicity
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