Physics Bucharest 2017

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Particle Therapy - Rational

Photons

p + , C 6+

1) Superior physical dose deposition properties

Exponential dose fall off after build up Inverse dose profile with a maximum energy deposition in the Bragg Peak → Dose at depth (target) is greater than dose at surface → Steep distal dose fall off (they stop)

2) Higher relative biological effectiveness (RBE)

Reference radiation RBE

RBE > 1

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