Physics Bucharest 2017

Carbon ions effectiveness

In-vivo Local control of 3 sublines of prostate carcinoma after 1 fx of photons and C-ions

> RBE

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+

Tumor resistance

• The response to C-ions is less dependent on resistance factors as well as on heterogeneity between and within tumor sublines as compared to photons. • Correlation between decreasing differentiation status and increasing RBE.

Glowa et al. Cancer Letters (378) 2016