PowerPoint Presentation

AK - Natural History

• Difficult to estimate the probability of AK to progress to invasive SCC • SCC in 6%-10% of immunocompetent patients with AK - in 40% of immunosuppresed patients • Risk of invasive SCC from a specific AK is highly variable (<1/1000 – 1.4%) • 60-80% of SCC originates from AK (length of time to progression: 2y)

Rigel e Stein Gold, JAAD 2013;68:S20-7