PowerPoint Presentation

Review of 24 studies which have evaluated the natural history of AK

• Progression rates per lesion/year: 0%-0.075% (0.53% in patients with history of NMSC) • Regression rate per lesion/year (15%-63% after 1y) with recurrent rates (15%-53%) • Variations re counting of AK in time: -53% - + 99.1% • Spontaneous remission in the field cancerization (0% - 21%) with recurrence (57%)