Quantitative Methods 2017

Risk of esophageal cancer following breast cancer according to radiotherapy dose Design Nested case–control study of esophageal cancer among 289 748 ≥5-year survivors of female breast cancer from five population-based cancer registries (252 cases, 488 individually matched controls), with individualized radiation dosimetry and information abstracted from medical records.

x j : clinical factors

j )  [1 + βz]

OR = exp(∑ j

α

x

j

z: radiation dose in Gy β: excess OR per Gy

0

ERR

FMB

Morton ML, Annals Oncol, 2012

Dose