Quantitative Methods 2017

CTCAEv4.0

Grading

Descriptions

Mild; asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated Moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental ADL Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of hospitalization indicated; disabling; limited self care ADL Life-threatening consequences; urgent intervention indicated

Grade 1

Grade 2

Grade 3

Grade 4 Grade 5

Death related to adverse event

Instrumental ADL: • Activities performed by a person who is living independently • During the course of a normal day • Examples: managing money, shopping, telephone use, travel in community, housekeeping, preparing meals, and taking medications correctly • More complex and are learned during teens