Quantitative Methods 2017

Grading according CTCAEv4.0

Endpoint with potential interobserver variability EXAMPLE: cheilitis Grading Descriptions Grade 1

Asymptomatic; clinical or diagnostic observations only; intervention not indicated

Grade 2 Grade 3 Grade 4 Grade 5

Moderate symptoms; limiting instrumental ADL

Severe symptoms; limiting self care ADL; intervention indicated

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