Quantitative Methods 2017

Model-performance Is the NTCP-model (standard IMRT-based) also with SW-IMRT

Standard IMRT cohort (n=305)

SW-IMRT cohort (n=186)

70%

70%

60%

60%

50%

50%

40%

40%

30%

30%

20%

20%

Observed incidence

Observed incidence

10%

10%

0%

0%

0% 10% 20% 30% 40% 50% 60% 70%

0% 10% 20% 30% 40% 50% 60% 70%

PredictedNTCP

PredictedNTCP

AUC: 0.80 (95% ci: 0.75-0.86)

AUC: 0.78 (95% ci: 0.69-0.86)

Christianen, et al. work in progress