Quantitative Methods 2017

Step 3: Clinical benefit Translate ΔDose into ΔNTCP

70%

Radiotherapie alleen Chemoradiation

60%

50%

Photons

40%

30%

NTCP (%)

Protons

20%

Translation from Δdose to ΔNTCP

10%

0% Risk tube feeding dependence (NTCP)

0 10 20 30 40 50 60 70 Gemiddelde dosis Mean dose superior PCM

Langendijk et al , Radiother Oncol 2013