Radiobiology 2016

2 nd cancers after RT of cervix Ca

Number of 2 nd cancers after radiotherapy/surgery

Site of second cancer

Radiation dose (Gy)

Relative risk afte r >10 years

2 after 10 y 4 after 30 y

Rectum

30–60

274 / 33

Colon

2 4

296 / 56

no increase

>2 after 10 y 6 after 30 y

Bladder

30–60

265 / 23

Stomach

2

143 / 19

1 . 2

Lung

0 . 3

276 / 91

no increase

decrease 20–40% after 10 y and 30 y

Breast

0 . 3

366 / 114

Leukaemia

4 . 5

82 / 15

2

Kleinerman RA et al. Cancer 1995;76:442-52