Radiobiology 2016

1/03/2016

Relevant radiobiological factors • Fractionation schedule: relation to EQD 2Gy

Yarnold Radiother Oncol 2005

α/β = 3 EQD 2Gy 39Gy/13fx 46.8Gy 50Gy/25fx 50Gy 42.9Gy/13fx 54Gy Alpha/beta value of 3.6 Gy (95% CI 1.8-5.4 Gy)

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Relevant radiobiological factors

• Fractionation schedule

Hypofractionated radiotherapy is safe and effective for patients with early breast cancer

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Haviland Lancet Oncol 2013

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