Radiobiology 2016

Meta-analysis on altered fractionation HNSCC Randomized trials 1970-1998 (no postop RT) 15 trials included (6515 patients, individual data)

100

100

p <0.0001

80

80

60

60

40

40

Overall survival

20

20

Loco-regional recurrence

0

0

ESTRO

Bourhis, Pignon 2006