Radiobiology 2016

a) Heterogeneity in hypoxia (%) amongst patients

20

Normal tissue

15

10

5

Relative frequency (%)

0

Nordsmark et al. Acta Oncol 1994

0

20

40

60

80

Oxygen partial pressure (mmHg)

100

80

20

Tumour

60

15

40

10

20

Dead (n=42) Alive (n=24)

5

0

Relative frequency (%)

Relative frequency patients (%)

0

0 10 20 30 40 50 60 70 80 90 100

20

40

60

80

0

Fraction pO 2

< 2.5 mmHg (%)

Oxygen partial pressure (mmHg)