Radiobiology 2016

Locoregional control

Overall survival

100

25 50 75 25 50 75

25 50 75 25 50 75

44% High

ll i l

39% High

29% Low -t

High vs Low -t p=0.01

38% Low +t

High vs Low -t p=0.03

Overall survival(%)

Low -t vs Low +t p=0.9

Low -t vs Low +t p=0.6

26% Low +t

35% Low -t

Low all vs High p=0.01

Low all vs High p=0.0005

0

0 0

0

0 12 24 36 48 60 Time after treatment (months)

0 12 24 36 48 60 Time after treatment (months)

Hoff et al Radiother Oncol 2010