Radiobiology 2016

Validation study in locally advanced HNSCC

Use of FDG-PET for target volume delineation in 3D- CRT/IMRT for head and neck tumors

• GTV-T

< GTV-T

FDG-PET

CT

• CTV-T

< CTV-T

FDG-PET

CT

• PTV-T

< PTV-T

(oropharyngeal SCC)

FDG-PET

CT

• More parotid sparing with the use of FDG-PET (oropharyngeal SCC)

• Loco-regional control probability within the expected range

ESTRO

Grégoire & Leclerc, 2013