Research Masterclass in Radiotherapy Physics 2017

Probabilistic p-TP for robust optimization

Analytical approach for uncertainty quantification and minization in particle therapy

Systematic errors: 3.5% Range, 1mm Setup Random errors: 1mm range, 2mm Setup

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M. Bangert, P. Hennig, U. Oelfke. Phys Med. Biol. 2013 N. Wahl, et al. Phys. Med. Biol. 2017

Page 35 Robust optimization allows for increased probability for coverage, smaller PTV, higher robustness Oliver Jäkel Medical Physics

Probabilistic proton dose calculation accounting for fractionation • Random and systematic uncertainties

1 fraction 5 s 103

Work by M. Bangert, et al.

Oliver Jäkel No y t implemented in any commercial TPS Medical Physics

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