Research Masterclass in Radiotherapy Physics 2017

Biophysics: modeling

• Aim at:

– Understanding mechanisms • A fitted model:

– will improve use of current treatments • Understanding a mechanism could: – change modeling approaches – treatments – impact other medical disciplines – True multi-disciplinarity (Epidemiology, Biology, Radiology, Other medical disciplines, …)

Heart-Lung work: - Calls for changes in optimization of thoracic RT (consider heart dose) - Identified new, serious, toxicity: Pulmonary hypertension - Yielded the 1 st animal model for human pulmonary arterial hypertension