SBRT 2016

Brain metastases NCCTG N0574 (Alliance): A phase III randomized trial of whole brain radiation therapy (WBRT) in addition to radiosurgery (SRS) in patients with 1 to 3 brain metastases Brown ASCO 2015 Cognitive function SRS SRS + WBI

deterioration @ 3 months immediate recall delayed recall verbal fluency

8%

31% 51% 19%

20%

2%

 Adverse effect of WBI on neurocognitive fraction already after 3 months

ESTRO SBRT COURSE 2016 - Matthias Guckenberger

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