SBRT 2016

Risk adapted fractionation – tumor location Central location

3 x 20 – 22Gy

~ 50% severe toxicity @ 2 years

Timmerman JCO 2006

5 x 10 – 12Gy

5 x 10-11Gy: 2 in 34 G3-5 Tox 5 x 11.5-12Gy: 13 in 86 G3-5 Tox

Chang JTO 2015

Bezjak IJROBP Supp 2015

• SBRT for central location - standard practice (Roesch submitted) • Optimal dose and definition of “too” central lacking

Matthias Guckenberger - ESTRO SBRT Course 2016 Athens

13.06.2016

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