Target Volume Determination 2015

T2 pre and post radiation

DWI pre and post radiation

Pre HIT

6 weeks post HIT 6 months post HIT

T2

DCE MRI

DWI

Pre

Post

Radiation-induced changes T2w pre IMRT

Oncological Guidelines: Imaging

Take home

• CT is limited for – T-stage

• CT of the abdomen • MRI of the pelvis • Chest x-ray if PSA > 20 ng/ml, or high risk patients • Bone scintigraphy if PSA > 10 ng/ml

– Extracapsular extension – N-stage • MRI method of choice for – T-stage – Extracapsular extension

1st post RT

2nd post RT

– Localization of leading tumor mass, if present • PET requires dedicated tracers for improved T- and N-staging

– C-11 Choline – Ga 68 PSMA

s.delorme@dkfz.de, Radiologie – E010, Innovative Krebsdiagnostik und -therapie