Target Volume Determination 2015

4D MRI – Breathing

4D MRI – Breathing

• Chest wall infiltration

• Tumor and atelectasis

Dynamic contrast-enhanced MRI

No Infiltration

Infiltration

Time-intensity curves

How it works: DCE MRI

Pharmakokinetic model

Contrast agent infusion

Color map

I

k pe

C 1

C 2

k ep

Central compartment

Peripheral compartment

1. Cycle 12 Slices

2. Cycle 12 Slices

3. Cycle 12 Slices

4. Cycle 12 Slices

Amplitude

Cl

k ep

Normal

Myeloma