Target Volume Determination 2015

CTV L2-L1: INDICATIONS

– No or inadequate lymphadenectomy (L) RT L4-L3-L2-L1 – Bulky nodal disease – SN (+) (Macrometastases) without lymphadenectomy. AMAROS Trial (EORTC) (Adjuvant Management of the Axilla Radiotherapy of Surgery) is comparing L vs axillary RT with SN (+). RT L4-L3-L2-L1 (Micrometastases: no RT) AMAROS Donker 2014 Lancet Oncol Including 4800 patients demonstrated that axillary RT is as effective as axillary surgery with less morbidity at 5 year follow-up.