Target Volume Determination 2015

CTV IM: INDICATIONS

• Controversy • IN FAVOR: ↓ LR Freedman / Gustave-Roussy / Veronessi / Hos t • AGAINST: No ↓ LR, fibrosis, cardiotoxicity Fowble / Obedian RT IM if SN (+) (histologically confirmed) in IM Locally advanced disease, medial tumour with positive axillary nodes

Trials: EORTC 22922 / Canadian NCIC MA20