Target Volume Determination 2015

CT and MRI

CT and MRI

PET

• T- and N-Staging

• T Staging

• N Staging

Sensitivity Specificity Accuracy CT 43-63% 84-97% 68-78%

Sensitivity Specificity Accuracy CT 46-91% 69-82% 65-84%

MRI

52-81% 80-96% 73-88%

MRI

48-93% 64-85% 61-84%

Musset et al 2003; Laurent et al, 1988; Grenier et al 1989; Webb et al 1991

Musset et al 2003; Laurent et al, 1988; Grenier et al 1989; Webb et al 1991

PET/CT

Determining GTV • Soft Tissue Delineation: Use Soft Tissue Window

Determining GTV • Delineation inside Lung: Use Lung Window

• N Staging

Sensitivity Specificity Accuracy CT 58-73% 65-76% 68-78%

PET/ CT

81-89% 83-91% 73-88%

• PET/CT correctly modified stage in 17% of patients • 2% were incorrect

Grosu et al Strahlenther Onkol 2005