Target Volume Determination 2015

Do we need adaptive radiotherapy?

PTV • Intra-fraction • Inter-fraction. • Tumor & OAR biology (multiparameter biologic image-defined). • Treatment dose. GTV CTV Adaptive radiation therapy “Adaptive radiotherapy is a close-loop radiation treatment process where the treatment plan can be modified using a systematic feedback of measurements.” (Yan et al, 1997) Measurements: • Tumor & OAR anatomy (position, shape & volume):

Yan et al. Phys Med Biol 1997;42:123-32.