Target Volume Determination 2015

• Whole brain or localised RT?

• Outcome studies suggest localised RT is as good for TCP

Marsa et al 256 pts, Cancer 1975; 36: 1681-89 Shapiro et al 571 pts randomised, J Neurosurg 1989; 71: 1-9 Kita et al 43 pts randomised, Gan No Rinsho 1989; 35: 1289-94