Target Volume Determination 2015

GTV delineation: PET & variability

• 10 GEJ ca undergoing RT • 6 Radiation Oncologists

Inter-observer variability

• CT alone vs PET-CT (manual)

• Median observer overlap analysis (bars = Observer Agreement Index) • Plans using PET-CT reduced both interobserver and intraobserver variability

Intra-observer variability PET-CT vs CT: 72.7% vs 69.1%

PET-CT vs CT: 78.7% vs 76.1%

Vesprini D. et al – Radiother Oncol. – 2010