Target Volume Determination 2015

after 2000 randomized trials

Short ERT

Trial

Winner

MRC C07 Duch Trial SURVIVAL no improvement

SC RT SC RT Local control improvement

SC RT+TME vs TME SC RT+TME vs TME

Long ERT

Trial

Winner

LC RT vs C-RT LC RT vs C-RT SC RT vs C-RT LC RT vs C-RT Acute Toxicity increased

C-RT C-RT C-RT =

FFCD 9203 Polish Trial EORTC 22921 Scandinavian TROG Trial