Upper GI 2016

State of art of radiation therapy in Esophageal Cancer ü Preoperative Chemoradiation à Planned Esophagectomy

• Walsh et al – 1996 (Trimodality) • Urba et al – 2001 (Trimodality) • Burmeister et al – 2005 (Trimodality) • Tepper et al – 2008 (Trimodality) • CROSS - 2015 (Trimodality) • FFCD 9901 - 2014 (Trimodality) • POET - 2009 (Trimodality)

SVV Benefit

NO SVV Benefit NO SVV Benefit

SVV Benefit

NO SVV Benefit NO SVV Benefit

SVV Benefit

ü Definitive Chemoradiation à Salvage Esophagectomy

SVV Benefit

• RTOG 85-01 - 1999 • INT 0123 - 2002

NO SVV Benefit

ü Chemoradiation à or Selective Esophagectomy

NO SVV Benefit NO SVV Benefit

• FFCD 9102 - 2015 • ESSEN Trial - 2005