Upper GI 2017

II

Design CRITICS-II

Preoperative chemotherapy 4x DOC q3 wks

D2 surgery

Staging laparoscopy

Preoperative chemotherapy 2x DOC q3 wks Chemoradiation ‘CROSS-regimen’ (45 Gy in 1.8 Gy/fx)

Chemoradiation ‘CROSS-regimen’ (45 Gy in 1.8 Gy/fx)

D2 surgery

R

D2 surgery

Tissue & blood banking