paediatrics Brussels 17

Anaplastic Wilms’ Tumor

• In NWTS-4, Stage I AH pts were treated with AMD and VCR and had 2-yr overall survival estimates of 85.5% to 93.3% depending on AMD administration regimen • Stage II to IV AH pts were treated with AMD, VCR and DOX and had 4-yr overall survival rate of 27.1% without CPM and 52.2% with CPM (p = 0.04)