paediatrics Brussels 17

IMPORT Study (UK) • Prospective clinical study (not RCT) • Aims to improve outcomes for WT and other childhood renal tumours by testing the feasibility of a more ‘personalised’ approach to risk stratification • Identification and refine new biomarkers (molecular, proteomic and imaging defined) for the management of the whole spectrum of childhood renal tumours • Biological characterisation of tumour, blood and urine samples • Central review of pathology and imaging • Treatment according to recently closed phase III SIOP Renal Tumours Study Group • Will inform design of future SIOP clinical trial, which will incorporate a more personalised assessment of relapse risk versus first line therapy burden