paediatrics Brussels 17

Quality control impact on pronostic

▪ Higher failure rates and worse overall survival in review of literature of several multicenter clinical trials Fairchild et al, IJROBP 2013

Peters et al, JCO 2010 Carrie et al, JCO 2009

▪ Meta analysis of RT-protocol deviations : occurred in 8–71% of cases, and were associated with a ~75% increased risk of treatment failure and overall mortality Ohri et al, JNCI 2013

▪ Use rapid web-based prospective online quality control