paediatrics Brussels 17

Table 1. Clinical and salvage treatment information for study patients

90 I. J. Radiation Oncology d Biology d Physics Volume 71, Number 1, 2008

Resection or metastasectomy results

RT2 irradiation sites

Maximal reirradiation dose (Gy) and site

Reirradiation volume

Lesions/ surgery sites

Interval RT1 RT2 (mo)

RT age (Y)

CSI dose (Gy)

RT2 failure

Patient

Site 1 (Gy)

Site 2 (Gy)

Site 3 (Gy)

1 2

SRS SRS

1/1 1/1

—

10.7 21.9

2.0 6.0

— Plneal(17.7) — CP angle (16.5)

— —

— Pineal (48)+17.5 SRS Combined

STR

— Cerebellum/stem

Local

(50.4) + 16.5 SRS

— 4 th ventricle (15.0)

3

SRS

1/1

STR

29.8

5.3

—

— Cerebellum/stem (60.4) + 15 SRS — Cerebellum/stem (69.6) + 18 SRS — Cerebellum/stem (50.4) + 18 SRS — Cerebellum/stem (90.4) + SRS — Cerebellum (113.4) — Temporal (108.4) — Cerebellum/stem (111.6) — Cerebellum/stem (113.4) — Cerebellum/stem (111.6) — frontotemporal(101.0) — Cerebellum/stem (109.4) — Cerebellum/stem (113.4) — Cerebellum/stem (113.4) — Cerebellum/stem (111.6) — Cerebellum/stem (120.0) — Cerebellum/stem (108.0) — no overlap

Local

— 4 th ventricle (18.0)

—

4

SRS

1/1

GTR

37.4

9.7

5

SRS

1/1

GTR

67.7

7.3

— Obex (18.0)

—

— 4 th ventricle (20.0) — 4 th ventricle (50.4) — 4 th ventricle (54.0) — Temporal (50.6) — Foramen rotundum (52.2) — 4 th ventricle (54.0)

6 7

SRS local

1/1 1/1

—

7.5

3.3

— —

Combined

GTR

75.7

10.1

8 9

local local local

1/1 1/1 1/1

NTR

10.5 14.1 14.1

4.3 9.5

— — —

—

Metastases Metastases

10

NTR

10.8

—

11

local

1/1

GTR

14.7

3.1

— 4 th ventricle (52.2)

12

local

1/1

NTR

17.1

6.2

—

Metastases

13

local

1/1

STR

23.1

5.3

— Left sylvlan

—

issue (50.6)

14

local

1/1

GTR

25.2

3.5

— CP angle (54.0)

—

— 4 th ventricle (54.0)

15

local

1/1

GTR

25.9

4.1

—

— 4 th ventricle (54.0)

16

local

1/1

GTR

22.0

3.5

—

— 4 th ventricle (52.2)

17

local

1/1

GTR

24.6

3.6

—

— 4 th ventricle (50.4)

18

local

1/1

GTR

82.2

9.9

—

— 4 th ventricle (54.0)

19

local

1/1

GTR

77.8

13.5

—

20

CSI

3/3

GTR

10.7

14.1 41.4 Frontal midline (57.6)

Occipital (57.6)

Parasagittal (57.6)

Frontal (111.6)

Combined

6.2 41.4 4 th ventricle (54.0)

Lateral ventricles (54)

L2L3 (54.0) Cerebellum/stem (113.4) + SRS

Local

21

CSI

5/3

STR

17.6

22 23 24

CSI CSI CSI

2/2 2/2 1/1

STR GTR GTR

20.1 33.9 50.9

16.9 39.6 Parietal (57.6) 4.8 35.2 Cerebellum (48.6) 10.0 38.6 Coolpital (59.4)

—

— Parietal (117.0)

Metastases

T4 (45.4)

— Cerebellum/stem (86.4)

—

— Occipital (113.4)

Local ( Continued )