paediatrics Brussels 17

Intracranial ependymoma

HIT 2000 / age : 4 – 21 years / M0 Ependymoma ° II/ ° III

RT tumour site only 68 Gy, 2 x 1.Gy / day (boost 72 Gy in persistent residual disease) weekly VCR in Gr. III

In grade III Chx HIT SKK 2000* 5x alternating CP/VCR

Surgery

CARBO/VP16 *no i.th. MTX

M 1 – 3 : RT CSA : 40 Gy hfx (2 x 1 Gy / day), boost tumour site 68 Gy, 72 Gy in persistent Tu., 50 Gy to spinal deposits + Chx. HIT SKK

HIT 2000 / age : < 4 years / M0

RT tumour site only 54 Gy, 5 x 1.8 Gy / week (stereotactic boost in pers.disease)

Regardless of grade Chx HIT SKK 2000*

Surgery

M 1 – 3 : RT CSA : 24 Gy, boost to tumour 54 gy + deposits 44.8Gy