paediatrics Brussels 17

Conclusion

• RT important; GTR important • RT dose-response relationship proven • Pattern of 1st relapse mainly local • M0: Local RT to 54-59.4 Gy standard today (age?) • CSI reserved for M+ disease • Role of Boost for residual disease (i.e. 2 x 4 Gy) ? • In recurrences again surgery plus RT (maybe even CSI as risk for dissemination seems to be quite high) • Modern techniques beneficial for volume reduction and improved feasibility