paediatrics Brussels 17

Medulloblastoma - Randomised Studies of Craniospinal RT Dose

• SIOP II (1984-1989) • 25 Gy - 55.3% 5 year EFS • 35 Gy - 67.6% 5 year EFS • p = 0.07 • POG/CCG (1986 - 1990) • 23.4 Gy - 52% 8 year EFS • 36.0 Gy - 67% 8 year EFS • p = 0.141