paediatrics Brussels 17

HIT/SIOP Study for Non-Metastatic (M0) Medulloblastoma (PNET-4)

• 2000 - 2006 • Can HFRT improve therapeutic ratio for RT?: • Can event-free survival be improved without an increase in neuropsychological long-term effects? • Standardised assessment of long-term effects - Health Utilities Index (HUI), endocrine assessment • Prospective evaluation of biological markers