paediatrics Brussels 17

SIOP-1

• 286 pts randomized to 30-45 Gy CSRT, 50-55 Gy PFRT +/- VCR + CCNU x 1 year • No difference in survival • Benefit in patients receiving chemotherapy in those with subtotal resection, brainstem involvement and T3 or T4 disease

Tait DM et al. Eur J Cancer 1990; 26:464-9