paediatrics Brussels 17

Proton Craniospinal Irradiation

Proton Photon

Weight loss > 5% p=0.004 Grade 2 nausea/ vomiting p=0.004 Esophagitis (medical management) p<0.001

16% 64%

26% 71%

5% 57%

Anemia p=0.04

17% 48%

Less Acute Toxicity

Brown AP et al. Int J Radiat Oncol Biol Phys 2013; 86:277-84