paediatrics Brussels 17

SIOP-PNET5-MB: Research study progress • Core panel sequencing methods • Define panels over Summer (post DFKZ meta-analysis)

WGS

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• On hold – need is dependent upon question. Reserve samples until resolved

• Links to QoS and pharmacogenomics studies • Not essential at outset – develop as trial progresses • Proposals in development: PNET4

Other studies:

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• Define as trial progresses / preliminary data becomes available (e.g. blood, CSF)

Funding

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• CRUK funding in place: core studies and international reference centre